Prevalence of diphtheria toxin antibodies in human sera from a cross-section of the Italian population.
نویسندگان
چکیده
A polycentric study was carried out between 1993 and 1995 in order to evaluate diphtheria immunity on a representative sample of population from different areas of Italy. To determine diphtheria antitoxin, sera from 5187 apparently healthy subjects, divided according to sex and age groups, were titrated using an ELISA indirect method. A basic protective titre of diphtheria antitoxin (> 0.01 IU ml-1) was found in 4080 (78.6%) subjects. No statistically significant differences between males and females were observed. Our findings show that the proportion of susceptibles increases with age and a high proportion of adults no longer has diphtheria antitoxin at protective levels since toxigenic C. diphtheriae circulation is presently lacking in Italy.
منابع مشابه
Tetanus and Diphtheria Seroprevalence in Patients Infected With Human Immunodeficiency Virus
Background and Objectives: HIV infected patients are at risk for vaccine-preventable infections such as tetanus and diphtheria (Td). In these patients, these antibodies tend to decline faster. Due to the limited data, this study assessed the seroprevalence of tetanus and diphtheria antibodies in HIV infected patients in Tehran, Iran. Materials and Methods: This case-control study was carried o...
متن کاملDistribution of Anti-leptospira Antibodies in the Sera of Patients Suspected Leptospirosis
Abstract Background and Objective: Leptospirosis is a zoonosis infectious disease that is prevalent in tropical and subtropical regions and is caused by the pathogenic serovars of leptospires. Hence, we aimed at investigating the prevalence of antibodies against these bacteria in the blood samples of suspected leptospirosis. Material and Methods: the human serum samples (N = 130) were ...
متن کاملDiphtheria antitoxin levels in the Netherlands: a population-based study.
In a population-based study in the Netherlands, diphtheria antitoxin antibodies were measured with a toxin-binding inhibition assay in 9, 134 sera from the general population and religious communities refusing vaccination. The Dutch immunization program appears to induce long-term protection against diphtheria. However, a substantial number of adults born before the program was introduced had n...
متن کاملSeroprevalence of Parvovirus B19 Antibodies in Young Women, Sanandaj, Iran
Background and Aims: Human parvovirus B19 may transmit to the fetus via the placenta during pregnancy and cause serious complications such as severe fetal anemia, non-immune hydrops fetalis, and even intrauterine fetal death. The aim of this study was to determine the seroprevalence of parvovirus B19 antibodies among young women, Sanandaj, Iran. Materials and Methods: Ninety young women (15-40 ...
متن کاملThe study of seroprevalence of human cytomegalovirus in healthy blood donors referring to Fars blood bank
Introduction: Human cytomegalovirus (HCMV) infection is most often asymptomatic in immuno-competent individuals and has lifelong latency especially in leukocytes. However, CMV is a major cause of infection and death in immuno-compromised patients. Transfusion transmitted HCMV (TT-HCMV) can cause serious morbidity and mortality in certain patients who are at risk. In this study, we evaluated t...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Vaccine
دوره 17 3 شماره
صفحات -
تاریخ انتشار 1999